国产精品99一区二区三_免费中文日韩_国产在线精品一区二区_日本成人手机在线

Way developed to determine effectiveness of drug-delivery nanoparticles: study

Source: Xinhua| 2019-08-11 04:09:36|Editor: Mu Xuequan
Video PlayerClose

CHICAGO, Aug. 10 (Xinhua) -- Researchers at Northwestern University (NU) have developed a way to determine whether or not single drug-delivery nanoparticles will successfully hit their intended targets of cancer biomarkers by simply analyzing each nanoparticle's distinct movements in real time.

By studying drug-loaded gold nanostars on cancer cell membranes, the researchers found that nanostars designed to target cancer biomarkers transited over larger areas and rotated much faster than their non-targeting counterparts.

Even when surrounded by non-specifically adhered proteins, the targeting nanostars maintained their distinct, signature movements, which suggest that their targeting ability remains uninhibited.

The medical field has long been searching for alternatives to current cancer treatments, such as chemotherapy and radiation, which harm healthy tissues in addition to diseased cells. Although these are effective ways to treat cancer, they carry risks of painful or even dangerous side effects.

By delivering drugs directly into the diseased area, instead of blasting the whole body with treatment, targeted delivery systems result in fewer side effects than current treatment methods.

"The selective delivery of therapeutic agents to cancer tumors is a major goal in medicine to avoid side effects," said Teri Odom, a professor of chemistry at NU's Weinberg College of Arts and Sciences, who led the study. "Gold nanoparticles have emerged as promising drug-delivery vehicles that can be synthesized with designer characteristics for targeting cancer cells."

"Moving forward, this information can be used to compare how different nanoparticle characteristics, such as particle size, shape and surface chemistry, can improve the design of nanoparticles as targeting, drug-delivery agents," said Odom.

The study was published Friday in the journal ACS Nano.

TOP STORIES
EDITOR’S CHOICE
MOST VIEWED
EXPLORE XINHUANET
010020070750000000000000011105091382994931
主站蜘蛛池模板: 紫金县| 全南县| 西青区| 延津县| 昂仁县| 昆山市| 黄大仙区| 巩留县| 赫章县| 始兴县| 长丰县| 景宁| 芒康县| 栾川县| 华池县| 涟水县| 清镇市| 固镇县| 望谟县| 微博| 泰和县| 登封市| 且末县| 柏乡县| 平顺县| 阜南县| 固始县| 安阳县| 江山市| 宝清县| 合山市| 独山县| 青龙| 广平县| 且末县| 漳州市| 会东县| 巴彦淖尔市| 桐庐县| 玛曲县| 霸州市|