国产精品99一区二区三_免费中文日韩_国产在线精品一区二区_日本成人手机在线

Way developed to determine effectiveness of drug-delivery nanoparticles: study

Source: Xinhua| 2019-08-11 04:09:36|Editor: Mu Xuequan
Video PlayerClose

CHICAGO, Aug. 10 (Xinhua) -- Researchers at Northwestern University (NU) have developed a way to determine whether or not single drug-delivery nanoparticles will successfully hit their intended targets of cancer biomarkers by simply analyzing each nanoparticle's distinct movements in real time.

By studying drug-loaded gold nanostars on cancer cell membranes, the researchers found that nanostars designed to target cancer biomarkers transited over larger areas and rotated much faster than their non-targeting counterparts.

Even when surrounded by non-specifically adhered proteins, the targeting nanostars maintained their distinct, signature movements, which suggest that their targeting ability remains uninhibited.

The medical field has long been searching for alternatives to current cancer treatments, such as chemotherapy and radiation, which harm healthy tissues in addition to diseased cells. Although these are effective ways to treat cancer, they carry risks of painful or even dangerous side effects.

By delivering drugs directly into the diseased area, instead of blasting the whole body with treatment, targeted delivery systems result in fewer side effects than current treatment methods.

"The selective delivery of therapeutic agents to cancer tumors is a major goal in medicine to avoid side effects," said Teri Odom, a professor of chemistry at NU's Weinberg College of Arts and Sciences, who led the study. "Gold nanoparticles have emerged as promising drug-delivery vehicles that can be synthesized with designer characteristics for targeting cancer cells."

"Moving forward, this information can be used to compare how different nanoparticle characteristics, such as particle size, shape and surface chemistry, can improve the design of nanoparticles as targeting, drug-delivery agents," said Odom.

The study was published Friday in the journal ACS Nano.

TOP STORIES
EDITOR’S CHOICE
MOST VIEWED
EXPLORE XINHUANET
010020070750000000000000011105091382994931
主站蜘蛛池模板: 偏关县| 莫力| 喀喇沁旗| 东台市| 湖州市| 瓦房店市| 普陀区| 拜泉县| 渭南市| 潮安县| 阿荣旗| 武威市| 莆田市| 洱源县| 襄樊市| 维西| 克东县| 宁明县| 屯门区| 漳州市| 肇州县| 苏尼特左旗| 涞水县| 嘉善县| 翁牛特旗| 临颍县| 项城市| 大田县| 新乐市| 深泽县| 砚山县| 阿克苏市| 和顺县| 江孜县| 西畴县| 安平县| 大石桥市| 兰州市| 砀山县| 武清区| 增城市|