国产精品99一区二区三_免费中文日韩_国产在线精品一区二区_日本成人手机在线

Aussie research gives hope for treatment of aggressive cancers

Source: Xinhua| 2019-05-28 19:16:53|Editor: huaxia
Video PlayerClose

SYDNEY, May 28 (Xinhua) -- An Australian study has identified a potential treatment method for aggressive cancer types, which currently leave sufferers with very few options.

Scientists from the Children's Medical Research Institute (CMRI) in Sydney and St Vincent's Institute of Medical Research (SVI) in Melbourne, said on Tuesday that they had successfully identified a mechanism to stop the reproduction of certain cancerous cells.

"Normal cells know when to stop dividing due to structures at the ends of chromosomes called telomeres," senior author, associate professor Hilda Pickett from CMRI, told Xinhua.

"Cancer cells overcome the telomeres telling them to stop dividing, essentially making them immortal."

To do this, around 40 percent of bone and soft tissue sarcomas use a mechanism called, alternative lengthening of telomeres (ALT).

"There are currently no specific therapies for ALT-positive sarcomas," co-author Dr Julienne O'Rourke from SVI said.

"People with this type of cancer have a 50-percent higher rate of death, as these cancers are more resistant to current treatments."

The team found that when they disrupt a particular protein called FANCM, which is essential for ALT cell viability, they could stop these types of cancer cells from dividing.

"We've understood what this protein does in these ALT cells and we've also used a drug which inhibits the function that's very specific to these ALT cancers," Pickett said.

While still in the very early stages of development, the team is hopeful that in the future their discovery could have a significant impact for those suffering these particularly aggressive cancers.

"This discovery is really the first hope to target ALT cancers, they will obviously need to be a lot of work to take it through to the clinic," Pickett said.

"We're all excited by the life-changing potential for people with these cancers; it's not every day you make discoveries that could lead to treatments that could save not a few, but many, precious lives." Enditem

KEY WORDS:
EXPLORE XINHUANET
010020070750000000000000011100001380972861
主站蜘蛛池模板: 祁东县| 静乐县| 锡林浩特市| 聂荣县| 百色市| 内江市| 民乐县| 元朗区| 丽水市| 罗甸县| 双鸭山市| 东港市| 车险| 吴川市| 迭部县| 商都县| 汉源县| 井陉县| 南陵县| 合阳县| 古交市| 榆树市| 安远县| 广德县| 徐闻县| 长乐市| 台安县| 吴江市| 会昌县| 邯郸县| 盐边县| 镇安县| 利川市| 阿拉善左旗| 保定市| 崇州市| 汪清县| 开化县| 秀山| 即墨市| 泰顺县|