国产精品99一区二区三_免费中文日韩_国产在线精品一区二区_日本成人手机在线

Overlooked signal in MRI scans reflects amount, kind of brain cells: study

Source: Xinhua| 2018-09-25 05:53:59|Editor: yan
Video PlayerClose

CHICAGO, Sept. 24 (Xinhua) -- Analyzing overlooked data from an MRI scan by a new technique developed by U.S. researchers surprisingly reveals how many and which brain cells are present, and shows where cells have been lost through injury or disease.

The researchers at Washington University School of Medicine in St. Louis analyzed the background data on an MRI scan and found a signal, which they called R2t*, that remained largely unchanged when people performed tasks but varied across parts of the brain.

They compared the R2t* signal with data from the Allen Human Brain Atlas, which maps genes active in various areas of the brain, and found three sets of gene networks that tracked with the R2t* signal.

These groups of genes, as it turned out, reflected the different kinds and numbers of brain cells, and the extent of connections between them.

In other words, this quick new MRI scan gave the researchers all they needed to know to determine how densely packed and interconnected the neurons are in any part of the brain.

The information could also help the researcher understand how a person's brain develops and changes from infancy to old age, and how human build memories and learn. It could also give clues to brain illness or injury.

"We did some studies on traumatic brain injury where we found some areas of the brain are already losing neurons even though the standard scans show nothing," said Dmitriy Yablonskiy, professor of radiology at the university's Mallinckrodt Institute of Radiology.

The researchers also applied their technique to the hippocampus, the memory center of the brain, in people with Alzheimer's disease. They found that not only was the hippocampus smaller than in healthy people, but the remaining part was not healthy: it had lost cells and begun to decay.

"There are MRI scans now that can detect brain atrophy even before people show symptoms of Alzheimer's disease," Yablonskiy said. "Our technique can show the brain degrading even before it begins to atrophy."

The researchers are now working on applying their technique to brain diseases and disorders including Alzheimer's, schizophrenia, multiple sclerosis and autism, as well as to understanding how a healthy brain develops and grows.

This eventually may lead to new ways to diagnose Alzheimer's disease, multiple sclerosis, traumatic brain injury, autism and other brain conditions through a simple brain scan.

The findings were published online the week of Sept. 24 in Proceedings of the National Academy of Sciences.

TOP STORIES
EDITOR’S CHOICE
MOST VIEWED
EXPLORE XINHUANET
010020070750000000000000011105521374904251
主站蜘蛛池模板: 广饶县| 广平县| 寻乌县| 民权县| 阿尔山市| 炉霍县| 彭山县| 怀仁县| 黄陵县| 井冈山市| 柳河县| 疏勒县| 许昌市| 白河县| 公安县| 东乌| 磴口县| 田林县| 芷江| 札达县| 行唐县| 栾城县| 威宁| 桓仁| 永平县| 巴青县| 册亨县| 柯坪县| 汉中市| 丹棱县| 锡林浩特市| 海城市| 嘉义县| 镇康县| 邹平县| 朝阳市| 布拖县| 洪洞县| 聂拉木县| 青浦区| 栾城县|