"/>

国产精品99一区二区三_免费中文日韩_国产在线精品一区二区_日本成人手机在线

Hormone points to better lung cancer chemotherapy treatment: Aussie research
Source: Xinhua   2018-07-26 12:24:16

SYDNEY, July 26 (Xinhua) -- A naturally occurring hormone could help make chemotherapy much more effective for many lung cancer patients, at the same time helping them avoid a kidney damage side effect from the usual treatment, according to Australian research findings released on Thursday.

When Professor Neil Watkins from the Garvan Institute for Medical Research and his team discovered that the protein activin was behind chemotherapy resistance and chemotherapy- induced kidney damage, it led them to develop the naturally occurring hormone follistatin - which blocks activin - to specifically treat inflammatory and fibrotic diseases.

Their lab tests on mice found that treatment of follistatin in combination with platinum- based chemotherapy caused lung tumors to shrink and more animals to survive longer, with kidney damage also prevented, the institute said in a statement.

"Because follistatin is a hormone already found in the human body, there is much less potential for toxicity than with other drugs used to reduce chemoresistance," said Watkins.

Research team member Kieren Marini said "discoveries like this one - a combination therapy that actually reduces damage while improving effectiveness of chemotherapy - are exceedingly rare in cancer research."

Their findings, published in the Science Translational Medicine medical journal, have laid the foundations to move this "combination therapy," of reducing damage while improving effectiveness of chemotherapy, to a clinical setting.

There are also plans to study other tumors where platinum chemotherapy is commonly used, such as bladder and head and neck cancers, said Watkins.

Editor: Liangyu
Related News
Xinhuanet

Hormone points to better lung cancer chemotherapy treatment: Aussie research

Source: Xinhua 2018-07-26 12:24:16
[Editor: huaxia]

SYDNEY, July 26 (Xinhua) -- A naturally occurring hormone could help make chemotherapy much more effective for many lung cancer patients, at the same time helping them avoid a kidney damage side effect from the usual treatment, according to Australian research findings released on Thursday.

When Professor Neil Watkins from the Garvan Institute for Medical Research and his team discovered that the protein activin was behind chemotherapy resistance and chemotherapy- induced kidney damage, it led them to develop the naturally occurring hormone follistatin - which blocks activin - to specifically treat inflammatory and fibrotic diseases.

Their lab tests on mice found that treatment of follistatin in combination with platinum- based chemotherapy caused lung tumors to shrink and more animals to survive longer, with kidney damage also prevented, the institute said in a statement.

"Because follistatin is a hormone already found in the human body, there is much less potential for toxicity than with other drugs used to reduce chemoresistance," said Watkins.

Research team member Kieren Marini said "discoveries like this one - a combination therapy that actually reduces damage while improving effectiveness of chemotherapy - are exceedingly rare in cancer research."

Their findings, published in the Science Translational Medicine medical journal, have laid the foundations to move this "combination therapy," of reducing damage while improving effectiveness of chemotherapy, to a clinical setting.

There are also plans to study other tumors where platinum chemotherapy is commonly used, such as bladder and head and neck cancers, said Watkins.

[Editor: huaxia]
010020070750000000000000011100001373494191
主站蜘蛛池模板: 宽甸| 怀宁县| 邢台县| 西藏| 宜黄县| 淮滨县| 崇左市| 镇平县| 连江县| 蛟河市| 靖安县| 新野县| 彝良县| 秦皇岛市| 达拉特旗| 岑巩县| 介休市| 望江县| 文登市| 兴安县| 浮山县| 肥城市| 长寿区| 神池县| 宣汉县| 甘肃省| 玉门市| 富川| 班玛县| 扎囊县| 佛冈县| 仙桃市| 西乌| 观塘区| 石渠县| 孝昌县| 友谊县| 绩溪县| 长白| 大宁县| 青阳县|