国产精品99一区二区三_免费中文日韩_国产在线精品一区二区_日本成人手机在线

Scientists take step forward in malaria vaccine using parasite mapping technique

Source: Xinhua| 2018-06-28 11:15:05|Editor: ZD
Video PlayerClose

SYDNEY, June 28 (Xinhua) -- Australian scientists on Thursday said they have taken a crucial step toward in developing a new malaria vaccine by using a novel "atomic-scale" blueprint to track how the parasite invades human cells.

"With this unprecedented level of detail, we can now begin to design new therapies that specifically target and disrupt the parasite's invasion machinery, preventing malaria parasites from hijacking human red blood cells to spread through the blood and, ultimately, be transmitted to others," Walter and Eliza Hall Institute of Medical Research Associate Professor Wai-Hong Tham said in a statement. Her team's discovery was published in scientific journal Nature.

The researchers' work involves using Nobel Prize-winning microscopy technology to map previously hidden first contact between the Plasmodium vivax malaria parasites and young red blood cells they invade that marks the start of the parasites' spread throughout the body, according to the research.

The "essential step in the malaria lifecycle is the beginning of the classical symptoms associated with malaria - fever, chills, malaise, diarrhoea and vomiting - which can last weeks or even longer," it said.

The Plasmodium vivax is the most widespread malaria parasite worldwide and the predominant cause of the major scourge in the vast majority of countries outside Africa, according to the institute.

The parasite's "propensity to 'hide' undetected by the immune system in a person's liver" also makes it "the number one parasite responsible for recurrent malaria infections."

The scientists, guided by their mapping technique, "was able to tease out the precise details of the parasite-host interaction, identifying its most vulnerable spots," said Tham, adding that they have "now identified the molecular machinery that would be the best target" for an anti-malarial vaccine against the widest range of the parasites.

TOP STORIES
EDITOR’S CHOICE
MOST VIEWED
EXPLORE XINHUANET
010020070750000000000000011100001372865031
主站蜘蛛池模板: 南宁市| 冕宁县| 夏邑县| 措勤县| 沙坪坝区| 根河市| 五常市| 德惠市| 普安县| 丰镇市| 葫芦岛市| 马关县| 东乡县| 罗甸县| 贡嘎县| 宜兰县| 林口县| 桦甸市| 闸北区| 微山县| 重庆市| 阿克陶县| 大安市| 依兰县| 崇信县| 霸州市| 响水县| 蚌埠市| 白朗县| 横峰县| 固安县| 涟源市| 清流县| 府谷县| 潍坊市| 黔东| 蓬莱市| 秀山| 山阴县| 镇康县| 旬阳县|