国产精品99一区二区三_免费中文日韩_国产在线精品一区二区_日本成人手机在线

Oncologists suggest new therapy by freezing cancer cells

Source: Xinhua| 2018-06-23 00:26:29|Editor: Chengcheng
Video PlayerClose

WASHINGTON, June 22 (Xinhua) -- American and Chinese oncologists suggested a potential therapy to freeze cancer cells before kill them where they stand.

A study published on Friday in the journal Nature Communications revealed the novel approach that can halt the movement of cancer cells before they spread throughout the body.

Raymond Bergan, professor of medicine at Oregon Health & Science University (OHSU) said that the majority of cancer treatment therapies were directed toward killing cancer but no one had developed a therapy that can stop cancer cells from moving around the body.

The study outlined a multidisciplinary team's work with KBU2046, a compound that was found to inhibit cell motility in four different human cell models of solid cancer types: breast, prostate, colon and lung cancers.

"Movement is key: the difference is black and white, night and day. If cancer cells spread throughout your body, they will take your life. We can treat it, but it will take your life," said Bergan.

Chemists led by Karl Scheidt, professor of chemistry at Northwestern University designed and created new molecules and Bergan's team evaluated them for their ability to inhibit cell motility.

Using chemical synthesis approaches, Scheidt and team accessed new compounds that minimized motility in tumor cells, with few side effects and very low toxicity.

"We started off with a chemical that stopped cells from moving, then we increasingly refined that chemical until it did a perfect job of stopping the cells with no side effects," said Bergan.

Bergan said the key to this drug was engaging the heat shock proteins or the "cleaners" of a cell. "The way the drug works is that it binds to these cleaner proteins to stop cell movement, but it has no other effect on those proteins."

The team of investigators includes Bergan's team at OHSU, a chemist from Northwestern University as well as researchers from Xiamen University in China, the University of Chicago, and the University of Washington.

"Our eventual goal is to be able to say to a woman with breast cancer: here, take this pill and your cancer won't spread throughout your body. The same thing for patients with prostate, lung, and colon cancer," Bergan said.

TOP STORIES
EDITOR’S CHOICE
MOST VIEWED
EXPLORE XINHUANET
010020070750000000000000011100001372743511
主站蜘蛛池模板: 清水河县| 青阳县| 温州市| 新竹县| 宜兴市| 兖州市| 温宿县| 甘洛县| 理塘县| 天柱县| 石城县| 阜康市| 福鼎市| 甘洛县| 呼图壁县| 固镇县| 化州市| 微博| 濉溪县| 神池县| 丰城市| 秦皇岛市| 神木县| 通河县| 黄山市| 武威市| 忻州市| 保定市| 会宁县| 灯塔市| 同心县| 武威市| 奉贤区| 西乌珠穆沁旗| 鱼台县| 同仁县| 启东市| 海晏县| 饶河县| 连州市| 双辽市|